Antithrombin iii human
Antithrombin iii human is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| thrombate iii | Biologic Licensing Application | 2010-01-10 |
Indications
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Clinical
Clinical Trials
5148 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 26 | 50 | 153 | 1 | 93 | 305 |
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | 3 | 36 | 43 | 74 | 148 | 301 |
| Neoplasms | D009369 | — | C80 | 46 | 46 | 92 | 7 | 76 | 246 |
| Thrombosis | D013927 | — | — | 22 | 36 | 75 | 47 | 65 | 235 |
| Thromboembolism | D013923 | HP_0001907 | — | 15 | 46 | 74 | 34 | 54 | 215 |
| Venous thromboembolism | D054556 | EFO_0004286 | I74 | 11 | 38 | 59 | 23 | 50 | 175 |
| Lymphoma | D008223 | — | C85.9 | 28 | 53 | 65 | 1 | 16 | 150 |
| Syndrome | D013577 | — | — | 16 | 29 | 43 | 17 | 38 | 136 |
| Venous thrombosis | D020246 | HP_0004936 | I82.40 | 9 | 20 | 55 | 18 | 37 | 132 |
| Leukemia | D007938 | — | C95 | 17 | 28 | 60 | 1 | 12 | 113 |
Show 224 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 26 | 73 | 93 | — | 48 | 218 |
| Non-small-cell lung carcinoma | D002289 | — | — | 25 | 77 | 98 | — | 35 | 214 |
| Carcinoma | D002277 | — | C80.0 | 22 | 53 | 111 | — | 27 | 191 |
| Healthy volunteers/patients | — | — | — | 125 | 5 | 4 | — | 14 | 148 |
| Melanoma | D008545 | — | — | 40 | 58 | 17 | — | 20 | 123 |
| Colorectal neoplasms | D015179 | — | — | 14 | 24 | 56 | — | 39 | 120 |
| Prostatic neoplasms | D011471 | — | C61 | 10 | 14 | 60 | — | 27 | 109 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 22 | 30 | 33 | — | 22 | 100 |
| Adenocarcinoma | D000230 | — | — | 17 | 26 | 42 | — | 9 | 86 |
| Ovarian epithelial carcinoma | D000077216 | — | — | 14 | 19 | 24 | — | 21 | 75 |
Show 733 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart arrest | D006323 | EFO_0009492 | I46 | — | 1 | — | — | 6 | 7 |
| Spinal muscular atrophy | D009134 | EFO_0003823 | G12.1 | 1 | 1 | — | — | 5 | 6 |
| Malocclusion | D008310 | HP_0000689 | M26.4 | — | 1 | — | — | 5 | 6 |
| Adenoma | D000236 | — | — | — | 1 | — | — | 4 | 5 |
| Joint diseases | D007592 | HP_0003040 | M12.9 | 1 | 2 | — | — | 3 | 5 |
| Laryngeal diseases | D007818 | — | J38.7 | 1 | 3 | — | — | 2 | 5 |
| Meningioma | D008579 | EFO_0003098 | D32.9 | — | 4 | — | — | 1 | 5 |
| Anxiety | D001007 | EFO_0005230 | F41.1 | 1 | 1 | — | — | 4 | 5 |
| Lobular carcinoma | D018275 | EFO_0000570 | — | 2 | 2 | — | — | 1 | 5 |
| Dentin sensitivity | D003807 | — | — | — | 1 | — | — | 4 | 5 |
Show 83 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | 1 | — | — | — | 8 | 9 |
| Coagulation protein disorders | D020147 | — | — | 3 | — | — | — | 4 | 7 |
| Inflammatory bowel diseases | D015212 | EFO_0003767 | — | 1 | — | — | — | 4 | 5 |
| Drug interactions | D004347 | — | — | 5 | — | — | — | — | 5 |
| Therapeutic equivalency | D013810 | — | — | 5 | — | — | — | — | 5 |
| Metabolic diseases | D008659 | EFO_0000589 | E88.9 | 1 | — | — | — | 4 | 5 |
| Hepatic insufficiency | D048550 | — | — | 3 | — | — | — | 1 | 4 |
| Crush injuries | D000071576 | — | T14.8 | 1 | — | — | — | 2 | 3 |
| Cigarette smoking | D000073865 | — | — | 1 | — | — | — | 2 | 3 |
| Suicide | D013405 | — | — | 1 | — | — | — | 2 | 3 |
Show 27 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cerebral palsy | D002547 | — | G80 | — | — | — | — | 14 | 14 |
| Exercise | D015444 | EFO_0000483 | — | — | — | — | — | 9 | 9 |
| Neck pain | D019547 | HP_0030833 | M54.2 | — | — | — | — | 8 | 8 |
| Paralysis | D010243 | HP_0003470 | — | — | — | — | — | 7 | 7 |
| Pressure ulcer | D003668 | — | — | — | — | — | — | 7 | 7 |
| Sedentary behavior | D057185 | — | — | — | — | — | — | 6 | 6 |
| Insulin resistance | D007333 | HP_0000855 | — | — | — | — | — | 5 | 5 |
| Prolapse | D011391 | — | — | — | — | — | — | 5 | 5 |
| Bursitis | D002062 | EFO_1000941 | M71.9 | — | — | — | — | 5 | 5 |
| Child development | D002657 | — | — | — | — | — | — | 5 | 5 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Antithrombin iii human |
| INN | antithrombin iii |
| Description | Thrombate III (antithrombin iii human) is an protein pharmaceutical. It is a concentrate of human antithrombin (AT) in lyophilized powder form for reconstitution for intravenous injection. |
| Classification | Protein |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108574 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | T0LTO7L82X (ChemIDplus, GSRS) |
Target
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Trends
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Safety
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123 adverse events reported
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